Genicular Nerve Radiofrequency Ablation

Genicular Nerve Radiofrequency Ablation (GNRFA) is a minimally invasive, image-guided procedure designed to relieve chronic knee pain caused by osteoarthritis and other degenerative conditions. By targeting the genicular nerves, which transmit pain signals from the knee joint to the brain, this technique reduces pain, improves joint mobility, and enhances quality of life.

Also known as genicular neurotomy, the procedure works by disrupting the pain pathways of the knee without affecting motor function. Using precise placement of specialized needles and electrodes under imaging guidance, radiofrequency energy is applied to selectively disable the nerves transmitting pain.

GNRFA has become an important option for patients seeking relief from knee osteoarthritis when medications, injections, and physical therapy have failed or when surgery is not desirable or possible. It can significantly reduce pain, restore activity, and delay or prevent the need for joint replacement.

When is Genicular Nerve Radiofrequency Ablation performed?

This treatment is typically recommended in case of:

  • Knee osteoarthritis with persistent pain not relieved by conservative measures.
  • Patients who are not candidates for surgery, or prefer to avoid knee replacement.
  • Patients who seek to reduce or eliminate reliance on pain medications, including opioids.
  • Patients who have persistent pain despite previous knee surgery.

In recent years, GNRFA has gained popularity as an effective alternative to surgery especially for individuals who wish to maintain an active lifestyle while avoiding the risks, costs, and prolonged recovery associated with joint replacement.

Understanding Genicular Nerve Radiofrequency Ablation

Who Is a Candidate for Genicular Nerve Radiofrequency Ablation?

Ideal candidates for GNRFA are patients who:

  • Suffer from chronic knee pain due to osteoarthritis or degenerative joint disease.
  • Have failed conservative treatments such as physical therapy, medications, or injections.
  • Have persistent pain even after joint replacement, or wish to avoid surgery altogether.
  • Show a positive response to a diagnostic nerve block (temporary pain relief after injection).
  • Are in good overall health and have realistic expectations about outcomes.

Preparing for Genicular Nerve Radiofrequency Ablation

Before the procedure, patients undergo a comprehensive consultation that includes:

  • A review of medical history and previous treatments.
  • Assessment of pain patterns and functional limitations.
  • Undergoing imaging tests (usually a CT angiogram) to plan the procedure.
  • Consideration of diagnostic nerve block results.

Key features of the procedure include:

  • Outpatient basis – patients return home the same day.
  • Local anesthesia – avoiding the risks of general anesthesia.
  • Minimal recovery time – most patients resume daily activities within days.
  • Lower costs – compared to surgical interventions.

What Happens During the Procedure?

  • You will be positioned on your back with the knee slightly bent.
  • The skin around the knee will be cleaned with antiseptic solution.
  • A diagnostic nerve block is performed to confirm the pain source. If pain reduces by ≥50%, ablation proceeds.
  • Under fluoroscopic or ultrasound guidance, thin cannulas are advanced to the target nerves.
  • A local anesthetic is applied, followed by insertion of a radiofrequency electrode.
  • Controlled radiofrequency energy is delivered to selectively disrupt the genicular nerves.
  • The cannulas are removed, and a small dressing is applied.

The entire process typically takes less than an hour.

After the Procedure

Patients are monitored briefly and discharged the same day. Mild soreness or muscle spasms may occur but usually resolve quickly.

Instructions include:

  • Keeping the incision site clean and dry.
  • Applying ice packs for comfort.
  • Avoiding heavy activity for 24–48 hours.
  • Gradually resuming walking and light exercise.

Post-Ablation Care and Recovery

  • Pain relief usually develops within a few days to weeks.
  • Relief may last 6–12 months or longer, depending on the patient.
  • Normal activity can usually resume the following day.
  • Some patients may require repeat treatment if nerves regenerate.

Tips for Recovery

  • Rest on the day of the procedure; increase activity gradually.
  • Use ice packs for swelling.
  • Take prescribed or recommended medications as directed.
  • Engage in physical therapy or gentle exercise, if advised, to maintain joint function.

Why Genicular Nerve Radiofrequency Ablation may be the best choice

  • Significant and sustained reduction in knee pain.
  • Improved joint function and mobility.
  • Outpatient, minimally invasive procedure.
  • Fewer risks than knee replacement.
  • Faster return to normal activity.
  • Can delay or eliminate the need for surgery.

By targeting the precise nerves responsible for pain, GNRFA offers patients a safe and effective way to regain mobility and independence.

Why Choose RIVEA?

At RIVEA Vascular Institute, we combine expertise with advanced technology to deliver world-class interventional pain management.

Led by Dr. Arjun Reddy, one of Hyderabad’s leading Interventional Radiologists, our team specializes in precision-guided, minimally invasive procedures that prioritize safety, comfort, and results.

What RIVEA offers:

  • Allia IGS 7 hybrid imaging system for precise minimally invasive procedures
  • High procedural expertise in image-guided embolization
  • Patient-first approach focused on comfort and fast recovery
  • One-on-one guidance from diagnosis through follow-up


Frequently Asked Questions (FAQ)

Is the procedure painful?

Most patients experience only mild discomfort during the procedure, managed with local anesthesia.

What is the success rate?

Clinical studies report that 50–70% of patients experience at least 50% pain relief for six months to over a year.

How long does relief last?

Relief typically lasts 6–12 months, and sometimes longer. Repeat procedures can restore benefits if pain returns.

Can it be repeated?

Yes, GNRFA can be safely repeated if needed.

What are the risks?

Complications are rare but may include:

  • Temporary soreness or swelling
  • Skin irritation at the treatment site
  • Rarely, tissue injury or difficulty localizing nerves

Who should avoid GNRFA?

Patients with:

  • Active knee infection
  • Uncontrolled diabetes
  • Implanted pacemakers (risk of interference)
  • Pregnancy
  • Unstable knee joint

Take the next step toward lasting relief from chronic knee pain.
Consult the specialists at RIVEA Vascular Institute, Hyderabad.

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Our Team

  • Dr. Arjun Reddy, expert in vascular and interventional radiology at RIVEA

    Dr. Arjun Reddy

    MBBS, MD, FVIR

    Dr. Arjun Reddy is a highly accomplished Interventional Radiologist with extensive international training and a track record of pioneering minimally invasive, image-guided procedures in India.

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